Genomics England
GMS Panels
Panels
Genes and Entities

TYK2

tyrosine kinase 2
OMIM: 176941
PanelMode of inheritanceDetails
1 panel
Green
in Primary immunodeficiency or monogenic inflammatory bowel disease
R-numbers: R15
Signed-off version 5.3
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Immunodeficiency 35 611521, Hyper IgE syndrome (HIES), Susceptibility to intracellular bacteria (mycobacteria, Salmonella), viruses, +/- elevated IgE, Defects in Intrinsic and Innate Immunity