Genomics England
GMS Panels
Panels
Genes and Entities

REN

renin
OMIM: 179820
PanelMode of inheritanceDetails
4 panels
Green
in Fetal anomalies
R-numbers: R21, R412
Signed-off version 4.0
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Renal tubular dysgenesis 267430
Green
in Paediatric disorders - additional genes
Component of the following Super Panels:
  • - Paediatric disorders
Signed-off version 4.3
BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Phenotypes
CAKUT, [Hyperproreninemia], Hyperuricemic nephropathy, familial juvenile 2, 613092, Renal tubular dysgenesis, 267430
Green
in Renal tubulopathies
Component of the following Super Panels:
  • - Unexplained young onset end-stage renal disease
R-numbers: R198
Signed-off version 4.18
BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Phenotypes
Hyperuricemic nephropathy, familial juvenile 2, 613092, Renal tubular dysgenesis 267430 AR
Green
in Tubulointerstitial kidney disease
Component of the following Super Panels:
  • - Unexplained young onset end-stage renal disease
R-numbers: R202
Signed-off version 3.4
BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal
Phenotypes
Renal tubular dysgenesis MIM 267430, Familial juvenile Hyperuricemic nephropathy-2 MIM 613092