Genomics England
GMS Panels
Panels
Genes and Entities

NEK8

NIMA related kinase 8
OMIM: 609799
PanelMode of inheritanceDetails
5 panels
Green
in Cystic kidney disease
Component of the following Super Panels:
  • - Cystic renal disease
Signed-off version 5.3
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Phenotypes
polycystic kidney disease, MONDO:0020642, ?Nephronophthisis 9, OMIM:613824
Green
in DDG2P
Component of the following Super Panels:
  • - Paediatric disorders
Signed-off version 4.3
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
RENAL-HEPATIC-PANCREATIC DYSPLASIA 2 615415, NEPHRONOPHTHISIS 9 613824
Green
in Fetal anomalies
R-numbers: R21, R412
Signed-off version 4.0
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
?Nephronophthisis 9, OMIM:613824, Nephronophthisis 9, MONDO:0013444, Renal-hepatic-pancreatic dysplasia 2, OMIM:615415, Renal-hepatic-pancreatic dysplasia 2, MONDO:0014174
Green
in Renal ciliopathies
Component of the following Super Panels:
  • - Cystic renal disease
  • - Paediatric disorders
  • - Rare multisystem ciliopathy Super panel
Signed-off version 3.6
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Renal-hepatic-pancreatic dysplasia, ?Renal-hepatic-pancreatic dysplasia 2, 615415, Nephronophthisis, ?Nephronophthisis 9, 613824
Green
in Unexplained young onset end-stage renal disease
R-numbers: R257
Signed-off version 4.4
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Ciliopathy genes associated with cystic kidney disease, ?Nephronophthisis 9, 613824?Renal-hepatic-pancreatic dysplasia 2, 615415