Genomics England
GMS Panels
Panels
Genes and Entities

ITK

IL2 inducible T-cell kinase
OMIM: 186973
PanelMode of inheritanceDetails
2 panels
Green
in Haematological malignancies cancer susceptibility
Signed-off version 4.0
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Class: miscellaneous, Lymphoproliferative syndrome 1, Hodgkins lymphoma
Green
in Primary immunodeficiency or monogenic inflammatory bowel disease
R-numbers: R15
Signed-off version 5.3
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Lymphoproliferative syndrome 1, Combined immunodeficiency, ITK deficiency (HLH phenotype), EBV viraemia, HLH, EBV associated B cell lymphoproliferation, lymphoma, Nl or low IgG, Diseases of Immune Dysregulation