Genomics England
GMS Panels
Panels
Genes and Entities

IRF6

interferon regulatory factor 6
OMIM: 607199
PanelMode of inheritanceDetails
5 panels
Green
in Arthrogryposis
R-numbers: R83
Signed-off version 6.3
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes
Popliteal pterygium syndrome 1 119500
Green
in Clefting
Component of the following Super Panels:
  • - Paediatric disorders
Signed-off version 5.3
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes
Orofacial cleft 6, 608864, Cleft Lip with or without Cleft Palate, Orofacial Clefting with skeletal features, Cleft lip +/- palate- unilateral or bilateral, cleft palate, lip pits, VAN DER WOUDE SYNDROME 1, VWS1, POPLITEAL PTERYGIUM SYNDROME, PPS, Cleft palate
Green
in DDG2P
Component of the following Super Panels:
  • - Paediatric disorders
Signed-off version 4.3
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes
VAN DER WOUDE SYNDROME 119300, POPLITEAL PTERYGIUM SYNDROME 119500
Green
in Fetal anomalies
R-numbers: R21, R412
Signed-off version 4.0
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes
POPLITEAL PTERYGIUM SYNDROME, VAN DER WOUDE SYNDROME
Green
in Van der Woude syndrome
R-numbers: R284
Signed-off version 1.0
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes